We thank Joshua Akey, professor of Genome Sciences at the UW and co–principal investigator on this project, for expert guidance on project design and statistical analysis; Hiroki Oura for development of the database and input on study design; and Joan Griswold, science education specialist at UW Genome Sciences, for insightful editing of this article. We also thank Drs. Debbie Nickerson and Gail Jarvik, who served as principal investigator and co–principal investigator, respectively, on the foundational project. This project was funded through an Innovative Technology Education for Students and Teachers (ITEST) grant from the National Science Foundation (NSF; DRL-0929181), which we gratefully acknowledge. The smoking behavior research study and database were developed through a Science Education on Drug Abuse Partnership Award from the National Institute on Drug Abuse, National Institutes of Health (NIDA, NIH; R25DA013180). The ideas presented in this paper represent the views of the authors and not necessarily those of the NSF, the NIDA, or the NIH.