CBE—Life Sciences EducationVol. 20, No. 3 General Essays and ArticlesFree AccessFostering Students’ Understanding of Complex Biological SystemsMelde G. R. Gilissen, Marie-Christine P. J. Knippels, and Wouter R. van JoolingenMelde G. R. Gilissen*Address correspondence to: Melde G. R. Gilissen (E-mail Address: [email protected]).Faculty of Science, Department of Mathematics, Freudenthal Institute, Utrecht University, 3844 CC Utrecht, The NetherlandsBonhoeffer College Bruggertstraat, 7545 AX Enschede, The Netherlands¶ORCIDs: 0000-0002-0668-4525Search for more papers by this author, Marie-Christine P. J. KnippelsFaculty of Science, Department of Mathematics, Freudenthal Institute, Utrecht University, 3844 CC Utrecht, The Netherlands§0000-0003-4989-1863Search for more papers by this author, and Wouter R. van JoolingenBonhoeffer College Bruggertstraat, 7545 AX Enschede, The Netherlandsǁ0000-0002-4271-2861.Search for more papers by this authorErika Offerdahl, Monitoring EditorPublished Online:28 Jun 2021https://doi.org/10.1187/cbe.20-05-0088AboutSectionsView articleView Full TextSupplemental MaterialView PDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InRedditEmail View articleSupplemental Materialcombinedsupmats.pdf (774 KB)FiguresReferencesRelatedDetailsCited byUsing Systems and Systems Thinking to Unify Biology EducationJennifer Momsen,Elena Bray Speth,Sara Wyse, and Tammy LongBrian Sato, Monitoring Editor2 May 2022 | CBE—Life Sciences Education, Vol. 21, No. 2Identifying knowledge important to teach about the nervous system in the context of secondary biology and science education–A Delphi study21 December 2021 | PLOS ONE, Vol. 16, No. 12 Vol. 20, No. 3 September 01, 2021 Supplemental MaterialsMetrics Downloads & Citations Citations: 2 History Submitted: 8 May 2020 Revised: 4 May 2021 Accepted: 18 May 2021 Information© 2021 M. G. R. Gilissen et al. CBE—Life Sciences Education © 2021 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).We are grateful to the school, the students, the observers, and especially the teachers for their contributions to this study. This research was supported by the Dutch Ministry of Education, Culture and Science through the Dudoc program.PDF download