We thank K. D. Tanner and E. D. Combs for making the BCST and analysis tools available to us and for productive conversations about their development and vetting of the BCST. E. D. Combs provided technical support for applying the Python scripts he developed. W. Ma of MSU’s Center for Statistical Training and Consulting provided statistical consultation. K. D. Tanner, C. M. Trujillo, and S. Wolf provided many helpful comments on an early draft of the paper. J. Abatie, K. Gordon, and T. Orlando helped with data entry. Finally, we are grateful to the introductory biology instructors and students who participated in this study and made this research possible. This work was supported under National Science Foundation DUE 08172224, Faculty Institutes for Reforming Science Teaching IV, D.E.-M. (principal investigator).