This material is based upon work supported by the National Science Foundation under grant no. 1458719. We are grateful to all the Bio101 instructors (Robert Dawley, Ellen Dawley, Cory Straub, Simara Price, and Biology faculty (Becky Kohn, Beth Bailey) for partnering with us in this effort. Thank you also to Robert Dawley for the exam autopsy and abbreviation. We thank Elizabeth Vallen for her counsel on best practices and for sharing resources. We are pleased to see student involvement in the work as well: Sinead O’Callaghan’s exam study plan and Maddy Wert’s idea to rename the exam autopsy as BIOpsy. We thank Cory Straub for his work on the analysis and reporting of supplemental instruction, which informed our discussions of the findings from the CoC program and Figure 1. We are indebted to Ann Breen for giving her time to independently analyze the study strategy data from pre and post assessments. We are grateful for Kevin Guidry’s thoughtful comments during survey development and program implementation.